Masayendisiti anowanzo kurudzira kusaongororwa masoja ekudzivirira chirwere mushure mekubaiwa.Asi kune vamwe vanhu, izvi zvine musoro.
Izvozvi makumi emamiriyoni evaAmerica vanobaiwa nhomba, vanhu vazhinji vanoda kuziva: Ndine masoja ekudzivirira chirwere akakwana here kuti ndichengetedzeke?
Kuvanhu vakawanda, mhinduro ndihungu.Izvi hazvina kumisa kuwanda kwemagwaro emuno mabhokisi ekuongororwa antibody.Asi kuti uwane mhinduro inovimbika kubva pakuyedzwa, munhu akabaiwa anofanira kuita bvunzo chaiyo panguva yakakodzera.
Edza nguva isati yakwana, kana kuvimba nebvunzo inotsvaga masoja ekudzivirira chirwere — izvo zviri nyore kufunga nezve dzungu remiyedzo iripo nhasi — unogona kufunga kuti uchiri panjodzi kana iwe usina.
Muchokwadi, masayendisiti anofarira kuti vanhuwo zvavo vakabayiwa nhomba havazoongororwa antibody zvachose, nekuti izvi hazvina basa.Mumiedzo yekiriniki, jekiseni rine rezenisi reUS rakakonzera mhinduro yakasimba yemasoja ekudzivirira chirwere munenge vatori vechikamu vese.
"Vanhu vazhinji havafanire kunetseka nezvazvo," akadaro Akiko Iwasaki, nyanzvi yekudzivirira zvirwere paYale University.
Asi kuongororwa kwemasoja ekudzivirira chirwere kwakakosha kune vanhu vane immune system isina simba kana avo vanotora mimwe mishonga - chikamu chakafara ichi chinosanganisira mamirioni anogamuchira zvipo zvenhengo, achirwara nemamwe magomarara eropa, kana kutora steroid kana mamwe anodzvanya immune system.Vanhu vane zvinodhaka.Pane humbowo huri kuramba huchiwedzera hunoratidza kuti chikamu chikuru chevanhu ava hachizogadzirise mhinduro yakakwana mushure mekubaiwa.
Kana uchifanira kuongororwa, kana kuti uchingoda kuongororwa, saka kuwana bvunzo yakakodzera kunokosha, Dr. Iwasaki akati: “Ndinozengurira kukurudzira munhu wose kuti aongororwe, nokuti kunze kwokunge vachinyatsonzwisisa basa rokuedza. , vanhu Inogona kudavira zvisiri izvo kuti hapana masoja ekudzivirira chirwere akagadzirwa.”
Mumazuva ekutanga edenda, bvunzo zhinji dzekutengesa dzaive dzakanangana nekutsvaga masoja ekudzivirira chirwere anorwisa puroteni inonzi nucleocapsid kana N, nekuti masoja ekudzivirira chirwere aya akawandisa muropa mushure mekutapukirwa.
Asi masoja ekudzivirira chirwere aya haana kusimba seaya anodiwa kudzivirira kutapukirwa nehutachiona, uye nguva yawo haina kurebesa kudaro.Zvinotonyanya kukosha ndezvokuti, masoja ekudzivirira chirwere anorwisa mapuroteni eN haabudiswe nemishonga inobvumidzwa neUnited States;pachinzvimbo, majekiseni aya anodenha masoja ekudzivirira chirwere anorwisa imwe puroteni (inonzi spikes) iri pamusoro pehutachiona.
Kana vanhu vasati vambobatwa nejekiseni vakabayiwa nhomba voongororwa masoja ekudzivirira chirwere anorwisa N protein pachinzvimbo chemasoja ekudzivirira chirwere anorwisa spikes, anogona kugadzirwa.
David Lat, munyori wezvemitemo ane makore makumi mana nematanhatu ekuzvarwa muManhattan akaiswa muchipatara Covid-46 kwemavhiki matatu munaKurume 2020, akanyora nezvehurwere hwake nekupora paTwitter.
Mugore rakatevera, VaRattle vakaongororwa zvirwere zvekudzivirira zvirwere kakawanda-somuenzaniso, pavakaenda kunoona chiremba wepulmonologist kana cardiologist kuti vatevere, kana kupa plasma.Antibody level yake yaive yakakwira muna Chikumi 2020, asi zvishoma nezvishoma yakadzikira mumwedzi yakatevera.
Rattle munguva pfupi yapfuura akarangarira kuti kudzikira uku “hakundinetse.”“Ndakaudzwa kuti zvichapera zvoga, asi ndinofara kuti ndichiri nemafungiro akanaka.”
Kubva munaKurume 22 gore rino, Mr. Lat vakabayiwa zvizere.Asi bvunzo yeantibody yakaitwa nachiremba wake wemoyo muna Kubvumbi 21 yakanga isina kunaka.VaRattle vakakatyamadzwa: “Ndaifunga kuti pashure pemwedzi wokubayiwa, masoja ekudzivirira chirwere angu aizoputika.”
VaRattle vakatendeukira kuTwitter kuti vatsanangure.Florian Krammer, nyanzvi yekudzivirira zvirwere paIcahn School of Medicine paGomo reSinai muNew York, akapindura nekubvunza kuti rudzii rwemuedzo wakashandiswa naVaRattle."Ndipo pandakaona ruzivo rwebvunzo," Mr. Rattle vakadaro.Akaona kuti uku kwaive kuyedza kweN protein antibodies, kwete masoja ekudzivirira chirwere anorwisa spikes.
"Zvinoita sekuti nekutadza, vanongokupa nucleocapsid," Mr. Rattle vakadaro."Handina kumbofunga kukumbira rimwe rakasiyana."
Muna Chivabvu wegore rino, iyo US Food and Drug Administration yakayambira kusashandisa bvunzo dzeantibody kuongorora kusadzivirirwa - danho rakakwezva kushoropodzwa kubva kune mamwe masayendisiti - uye rakangopa ruzivo rwekutanga nezve bvunzo kune vanopa hutano.Vanachiremba vazhinji havasati vaziva mutsauko uripo pakati pekuongororwa kwemasoja ekudzivirira chirwere, kana nyaya yekuti bvunzo idzi dzinoyera nzira imwe chete yekusadzivirirwa kuhutachiona.
Kazhinji inowanikwa yekukurumidza bvunzo inopa hongu-kwete mhinduro uye inogona kupotsa yakadzikira masoja ekudzivirira chirwere.Imwe mhando yebvunzo yemurabhoritari, inodaidzwa kuti Elisa bvunzo, inogona kuita semi-quantitative fungidziro ye spike protein antibodies.
Izvo zvakakoshawo kumirira angangoita mavhiki maviri kuti uedzwe mushure mejekiseni rechipiri rePfizer-BioNTech kana Moderna vaccine, apo mazinga ekudzivirira muviri achakwira kusvika padanho rinokwana kuonekwa.Kune vamwe vanhu vanogamuchira yekudzivirira yeJohnson & Johnson, nguva iyi inogona kunge yakareba semavhiki mana.
"Iyi ndiyo nguva, antigen uye kunzwa kwekuedzwa-izvi zvose zvakakosha," akadaro Dr. Iwasaki.
Muna Mbudzi, World Health Organisation yakamisa mazinga ekuyedza maantibody kuti abvumire kuenzanisa kwebvunzo dzakasiyana."Kune miedzo yakawanda yakanaka ikozvino," Dr. Kramer akadaro."Zvishoma nezvishoma, vese vagadziri ava, nzvimbo dzese idzi dzinovafambisa dziri kuchinjika kune dzimwe nyika."
Dr. Dorry Segev, chiremba anovhiyiwa uye muongorori paJohns Hopkins University, akataura kuti masoja ekudzivirira chirwere anongova chikamu chimwe chete chekurwisa utachiona hwezvirwere: “Zvinhu zvakawanda zvinoitika pasi pevhu izvo zvisingagone kuyerwa zvakanangana nekuongorora masoja emuviri.Muviri uchiri kuchengetedza iyo inonzi cellular immune, inova Iyo yakaoma network yevadziviriri ichapindurawo kune vanopinda.
Vati zvisinei, kune vanhu vanenge vabaiwa nhomba asi vasisina simba rekudzivirira zvirwere, zvinogona kubatsira kuziva kuti kudzivirira kubva kuutachiona handiko kwazvinofanira kuva.Semuyenzaniso, murwere anotapurirana ane mazinga asina kunaka ekurwisa masoja anogona kukwanisa kushandisa mhinduro dzebvunzo kugonesa mushandirwi kuti arambe achishanda ari kure.
VaRattle havana kutsvaga imwe bvunzo.Zvisinei nemhedzisiro yebvunzo, kungoziva kuti jekiseni rinogona kuwedzera masoja ekudzivirira chirwere zvakare zvakakwana kumusimbisa: "Ndinotenda kuti jekiseni rinoshanda."
Nguva yekutumira: Jun-23-2021