Int J Infect Dis.Chikumi 20, 2021: S1201-9712(21)00520-8.doi: 10.1016/j.ijid.2021.06.031.Online isati yadhinda.
Background: Neutralization antibodies (NAbs) yakakosha kudzivirira kutapukirwa neCOVID-19.Takafananidza bvunzo mbiri dzakabatana neNAb, iyo hemagglutination bvunzo (HAT) uye yekutsiva hutachiona neutralization test (sVNT).
Nzira: Iyo chaiyo yeHAT yakaenzaniswa nesVNT, uye kunzwisisika uye kusimba kwezvirwere muvarwere vane zvirwere zvakasiyana-siyana zvakaongororwa muboka revarwere ve71 pa4 kusvika kumavhiki e6 uye 13 kusvika kumavhiki e16.Kinetic assessment yevarwere vane zvirwere zvakakomba zvakasiyana-siyana yakaitwa mumavhiki ekutanga, echipiri uye echitatu.
Results: Iyo chaiyo yeHAT ndeye> 99%, uye senitivity yakafanana neye sVNT, asi yakaderera pane iyo ye sVNT.Chiyero cheHAT chakanyatsoenderana nechiyero che sVNT (Spearman's r = 0.78, p <0.0001).Kuenzaniswa nevarwere vane chirwere chakapfava, varwere vane chirwere chepakati uye chakakomba vane HAT titers yakakwirira.6/7 varwere vanorwara zvakanyanya vaiva netiter ye> 1: 640 muvhiki yechipiri yekutanga, asi 5 / 31 chete varwere vanorwara zvishoma vaiva netiter ye> 1: 160 muvhiki yechipiri yekutanga.
Mhedziso: Sezvo HAT iri nyore uye yakachipa nzira yekuona, yakanaka sechiratidzo cheNAb munzvimbo dzisina zviwanikwa.
Nguva yekutumira: Jun-25-2021